In vitro fertilization, ICSI requires just one sperm cell to produce an embryo.
This intracytoplasmic sperm injection technique is, therefore particularly indicated for male infertility treatment Pakistan problems in several cases:
Asthenospermia (or asthenozoospermia)
Commonly known as “lazy sperm syndrome,” this form of male infertility causes an abnormality in the sperm that affects sperm mobility and can compromise natural fertilization. Following a fertility plan by opting for IVF ICSI can increase the chances of fertilization in cases of asthenospermia.
In cases of severe oligospermia, where the number of sperm cells collected is very low (less than 1 million sperm per milliliter of semen), IVF ICSI with intracytoplasmic microinjection is particularly indicated. An insufficient sperm count compromises the chances of success of conventional IVF.
What is the IVF ICSI protocol?
Apart from the in vitro fertilization process, which differs, the ICSI IVF procedure is very similar to conventional IVF. It begins with ovarian stimulation in the woman to stimulate the growth of as many oocytes as possible. These are retrieved by egg retrieval. At the same time, the sperm is collected. Oocytes and the sperm cells are ready: the fertilization process using intracytoplasmic sperm injection (IVF ICSI) can occur.
During IVF ICSI, in vitro fertilization is carried out under a microscope:
A micropipette is used to hold the oocyte by suction (on the left of the photo). At the same time, the sperm cell is selected and aspirated into the injection pipette (on the right of the image). This selection is based on morphological and mobility criteria. It is then reinjected into the oocyte. Signs of fertilization and embryonic development are observed the following day of transfer.
IVF ICSI: success rate?
In 2024, according to the Biomedicine Agency’s medical and scientific report, 7,863 Pakistani were achieved following 43,254 ICSI IVF attempts. The IVF ICSI success rate (number of births per number of attempts) is 18.1%.
A study in the United Kingdom showed that ICSI IVF increased in vitro fertilization rates compared with conventional IVF (82.7% vs. 67.0%). ivf treatment pakistan is the in vitro fertilization technique that offers the greatest chance of success during fertility treatment.
